O-PCE

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O-PCE (2-Oxo-PCE) is a potent dissociative compound for NMDA receptor research. Offered as high-purity powder for analytical lab studies only.

Product Information Table

Property Value
Product Name O-PCE (2-Oxo-PCE)
CAS Number 90740-54-6
IUPAC Name 2-(ethylamino)-2-phenylcyclohexanone
Molecular Formula C14H21NO
Molecular Weight 219.33 g/mol
Form Crystalline powder
Purity ≥98%
Appearance White to off-white solid
Applications NMDA receptor research, glutamate pathways
Storage Store sealed, in cool, dark, dry conditions

Buy O-PCE – High-Purity Dissociative Research Chemical

O-PCE, or 2-Oxo-PCE, is a dissociative arylcyclohexylamine compound belonging to the eticyclidine class, structurally related to MXE and 3-MeO-PCP. It is often studied for its interaction with NMDA receptors and is used in controlled environments for neurological, pharmacological, and receptor-based research.

Offered in high-purity crystalline powder form, O-PCE is ideal for labs focused on mapping glutamatergic system interactions, CNS dissociation mechanisms, and neuroreceptor modulation studies. It is strictly intended for research use only and is not approved for human or veterinary consumption.


  Key Product Details

  • Chemical Name: 2-Oxo-PCE

  • IUPAC Name: 2-(ethylamino)-2-phenylcyclohexanone

  • Common Name: O-PCE

  • CAS Number: 90740-54-6

  • Molecular Formula: C14H21NO

  • Molecular Weight: 219.33 g/mol

  • Form: Crystalline powder

  • Purity: ≥98%

  • Appearance: White to off-white solid

  • Application: Dissociative receptor studies, NMDA research

  • Storage: Store in a cool, dry, sealed container

  • Legal Status: For laboratory use only; not for human ingestion


 How It Works

O-PCE acts primarily as an NMDA receptor antagonist, similar in mechanism to ketamine and PCP derivatives. In laboratory research, O-PCE blocks the N-methyl-D-aspartate (NMDA) receptors, a subtype of glutamate receptor involved in synaptic plasticity, pain modulation, and memory function.

This antagonism results in:

  • CNS dissociation effects in vitro

  • Suppression of excitatory neurotransmission

  • Potential neuroprotective responses in simulated models

Due to its potent activity and minimal metabolism in some animal models, O-PCE is used for time-course receptor binding and neurochemical interaction mapping.


⚠️ Safety and Warning Guidelines

  • Lab Use Only: O-PCE is not approved for human or animal use. For certified laboratory research only.

  • PPE Required: Always wear gloves, eye protection, and a lab coat.

  • Handling Advice: Use only in ventilated environments under fume hoods.

  • Storage: Store in sealed containers in a dry, cool place, away from light.

  • Disposal: Follow institutional guidelines and hazardous waste disposal protocols.

  • Regulatory Compliance: Responsibility lies with the researcher to confirm legal status before purchase or use.

  • Exposure Protocol: In case of skin or eye contact, wash thoroughly and seek medical advice if irritation occurs.


🔍 Research Applications of O-PCE

  • NMDA receptor binding studies

  • Investigation of glutamate-modulated neurotransmission

  • Pharmacological modeling of dissociative compounds

  • Cross-comparison with MXE, PCP, and ketamine analogs

  • Simulation of neuroprotective pathways in CNS injury models


⚠️ Usage Disclaimer

This compound is supplied strictly for scientific research and forensic analysis. It is not for human or animal consumption under any circumstances.


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