Buy O-DSMT HCL – High-Purity O-Desmethyltramadol for Scientific Research

O-DSMT HCL (O-Desmethyltramadol Hydrochloride) is a primary active metabolite of Tramadol, widely studied for its role in mu-opioid receptor activity and serotonin/norepinephrine reuptake inhibition. Offered in high-purity hydrochloride salt form, this compound is ideal for analytical, pharmacological, and biochemical studies.

Due to its dual activity profile, O-DSMT HCL is a valuable tool in receptor binding assays, neurochemical modeling, and pain modulation pathway research. It is not intended for human consumption, and should only be used by certified professionals in a lab environment.

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  Key Product Details

• Chemical Name: O-Desmethyltramadol Hydrochloride

• IUPAC Name: (±)-cis-2-[(dimethylamino)methyl]-1-(3-hydroxyphenyl)cyclohexanol hydrochloride

• Common Name: O-DSMT, O-Desmethyltramadol HCL

• CAS Number: 73986-66-4

• Molecular Formula: C16H25NO2 · HCl

• Molecular Weight: 299.84 g/mol

• Form: Crystalline powder

• Purity: ≥98%

• Appearance: White to off-white powder

• Application: Laboratory and analytical research

• Storage: Store in a sealed container, cool, dry place

• Legal Status: Research use only – not approved for human or animal use

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  How It Works

O-DSMT is an active metabolite produced from Tramadol via demethylation. It has been shown in laboratory settings to act primarily as a mu-opioid receptor agonist, and secondarily as a serotonin-norepinephrine reuptake inhibitor (SNRI).

Its dual binding activity allows researchers to explore:

• Opioid receptor affinity

• CNS-mediated pain modulation

• Neurochemical transporter inhibition

• Structure-activity relationships (SAR) of atypical opioids

The hydrochloride salt form enhances stability and solubility, making it suitable for in vitro assays and receptor binding experiments.

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⚠️ Safety and Warning Guidelines

• Research Use Only: This compound is not intended for human ingestion or therapeutic application.

• Handling Precautions: Use gloves, goggles, and a lab coat. Avoid inhalation and skin exposure.

• Working Environment: Use only in ventilated fume hoods with secure handling protocols.

• Storage Conditions: Store in a dry, cool, and dark location in an airtight container.

• Disposal: Dispose of in accordance with hazardous waste regulations and institutional protocols.

• Regulatory Responsibility: Ensure legality in your region. May fall under analog laws or controlled substance acts.

Strictly for use by qualified laboratory professionals. Misuse may be hazardous to health and is illegal in many jurisdictions.

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 Research Applications of O-DSMT HCL

• Receptor affinity mapping (μ-opioid receptor studies)

• Neurochemical transporter interaction modeling

• Comparative metabolite pharmacokinetics

• SAR research on synthetic analgesic analogs

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⚠️ Usage Disclaimer

This product is intended for laboratory research use only. It is not for human or veterinary consumption. Use only in certified scientific environments.

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